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Tyrosine 251 at the C-terminus of Neuronal Glycoprotein M6a is Critical for Neurite Outgrowth
(Wiley-liss, Div John Wiley & Sons Inc, 2015-09)
Neuronal glycoprotein M6a is involved in neuronal plasticity, promoting neurite and filopodia outgrowth and, likely, synaptogenesis. Polymorphisms in the human M6a gene GPM6A have recently been associated with mental ...
Selective Cre-mediated gene deletion identifies connexin 43 as the main connexin channel supporting olfactory ensheathing cell networks
(Veterinary and Human Toxicology, 2019-05)
Many functions of glial cells depend on the formation of selective glial networks mediated by gap junctions formed by members of the connexin family. Olfactory ensheathing cells (OECs) are specialized glia associated with ...
Filopodia formation driven by membrane glycoprotein M6a depends on the interaction of its transmembrane domains
(Wiley Blackwell Publishing, Inc, 2015-08)
Membrane glycoprotein M6a, which belongs to the tetraspan proteolipid protein family, promotes structural plasticity in neurons and cell lines by unknown mechanisms. This glycoprotein is encoded by Gpm6a, a stress-regulated ...
Identificación y caracterización de ligandos/proteínas que interactúen con los dominios extracelulares de la glicoproteína de membrana neuronal M6a.
(Universidad Nacional de San Martín. Escuela de Bio y Nanotecnologías. Instituto de Investigaciones Biotecnológicas., 2022)
Identification of Potential Interacting Proteins With the Extracellular Loops of the Neuronal Glycoprotein M6a by TMT/MS
(Frontiers Media S.A., 2020-07)
Nowadays, great efforts are made to gain insight into the molecular mechanisms that underlie structural neuronal plasticity. Moreover, the identification of signaling pathways involved in the development of psychiatric ...
Evidence for a role of glycoprotein M6a in dendritic spine formation and synaptogenesis
(Academic Press Inc Elsevier Science, 2016-12)
Neuronal glycoprotein M6a belongs to the tetraspan proteolipid protein (PLP) family. Mutations in GPM6A gene have been related to mental disorders like schizophrenia, bipolar disorders and claustrophobia. M6a is expressed ...
Altered expression of neuroplasticity-related genes in the brain of depressed suicides
(Pergamon-Elsevier Science Ltd, 2015-07)
Background: Expression of the neuronal membrane glycoprotein M6a (GPM6A), the proteolipid protein (PLP/DM20) family member, is downregulated in the hippocampus of chronically stressed animals. Its neuroplastic function ...
Problemas taxonômicos da família Threskiornithidae: filogenia molecular e o caso de Eudocimus
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, 2011-03-01)
The family Threskiornithidae includes 13 genera and 32 species, but the relationships among genera, species or subspecies have been little studied. This family is traditionally divided into two subfamilies: Plataleinae and ...
Clinical Features And Management Of Hereditary Spastic Paraplegia [aspectos Clínicos E Manejo Das Paraplegias Espásticas Hereditárias]
(Arquivos de Neuro-Psiquiatria, 2014)